L1000

The L1000 dataset consists of ~1,400,000 gene-expression profiles on the responses of ~50 human cell lines to one of ~20,000 compounds across a range of concentrations. The L1000 dataset and its normalization versions10 were recently widely used in drug repurposing and discovery.

Description from: A deep learning framework for high-throughput mechanism-driven phenotype compound screening and its application to COVID-19 drug repurposing

Publication introducing the dataset: A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles